RESEARCH
Several research projects are being carried out in the department. Majority of these are investigator initiated and some of them are multicentric.
PROJECTS
|
Title of Project and investigators |
Date of Starting |
Funding body |
---|---|---|---|
Ongoing Projects |
|||
1 |
Concomitant chemoradiotherapy versus accelerated radiotherapy versus conventional radiotherapy in the management of advanced carcinoma of the head and neck. S. (Ghosh) Laskar, JP Agarwal, TK Saikia, KA Dinshaw |
2000 |
TMH/ CSIR |
2 |
Randomized multicentric study of 5 v/s 6 weekly fractions of radiotherapy in the treatment of squamous cell carcinoma of head & neck. JP Agarwal, SK Shrivastava, S (Ghosh) Laskar, KA Dinshaw |
2000 |
IAEA/TMH |
3 |
Intraoperative Iridium - 192 tumor bed implant alone in early breast cancer. Sarin R, Jalali R, Budrukkar AN, Badwe R, Parmar V, Nadkarni M, Chinoy R, Shet T, Shrivastava SK, Deshpande DD, Dinshaw KA |
2001 |
Nil |
4 |
HDR Brachytherapy Of Internal Mammary Nodal Chain In Breast Cancer With Intra-Operative Catheter Placement In The Internal Mammary Vessels. Sarin R, Badwe R, Jalali R, Mahantshetty U, Budrukkar A, Parmar V, Nadkarni M, Deshpande DD |
2001 |
Nil |
5 |
Feasibility study to evaluate and correlate between clinical & sonographic responses in cervical node metastases in head & neck carcinoma following radical radiotherapy. S (Ghosh) Laskar, JP Agarwal, S Arya, T Pandey, P Corea |
2002 |
TMH |
6 |
Concomitant chemoradiation in advance stage carcinoma cervix- A phase III Randomised trial. SK Shrivastava, HB Tongaonkar, S Gupta, R Kerkar, A Maheshwari, S (Ghosh) Laskar, KA Dinshaw |
2003 |
TMH/ ICMR |
7 |
Concomitant chemoradiation versus neo-adjuvant chemotherapy and surgery in the management stage II carcinoma cervix- A phase III Randomised trial, S Gupta, HB Tongaonkar,SK Shrivastava, eshwari, S (Ghosh) Laskar, KA Dinshaw |
2003 |
TMH/ ICMR |
8 |
Intraluminal HDR brachytherapy alone versus Intraluminal HDR brachytherapy and External Beam Radiotherapy in the Palliation of Advanced Oesophageal Carcinoma. KA Dinshaw, S Ghosh Laskar, SK Shrivastava, DD Deshpande, RA Kinnhikar |
2003 |
IAEA/TMH |
9 |
Two vs four cycles of abvd chemotherapy and low dose radiation therapy in early stage favourable prognosis hodgkin's disease: a randomised clinical trial.M.A.Muckaden, .S. Laskar, T.K.Saikia, S.K.Pai, K.Naresh, S.Gupta |
2003 |
TMH |
10 |
Hereditary Cancer Consortium. R Sarin, SS Agarwal, KA Dinshaw K Mohandas, P Kurkure, R Badwe, H Tangaoankar, A Puri, R Chinoy, R Mulherkar, P Kadam |
2002 |
TMH |
11 |
Accelerated Tumor Bed Irradiation in Early breast cancer with IMRT: A Feasibility and dosimetric study. R Sarin S Chopra, D Kumar, SS Narayanan, R Kamble, R Jalali, SK Shrivastava, DD Deshpande, K A Dinshaw |
2003 |
TMH |
12 |
Efficacy of stereotactic conformal radiotherapy (SCRT) compared to conventional radiotherapy in minimising late sequelae in children and young adults with brain tumours: a randomised clinical trial (SCRT trial). R Sarin, R Jalali, N Merchant, S Goswami, N Shah, KA Dinshaw, et al |
2001 |
Terry Fox Foundation |
13 |
To prospectively compare tumour control, late sequalae and quality of life in patients with non-functioning pituitary adenomas treated with surgery alone versus surgery followed by radiotherapy: a randomised trial (pituitary trial). R Jalali, A Goel, R Sarin, et al |
2002 |
TMH |
14 |
Radioprotective effect of ocimum sanctum (Tulsi) in patients undergoing hemibody irradiation: A double blind randomised trial R Sarin, R Jalali, SK Shrivastava, MA Muckaden, M Ghatge, AS Raste, KA Dinshaw |
2002 |
ICMR grant |
15 |
Prevalence and spectrum of BRCA1 and BRCA2 mutations in familial breast ovarian cancers. R Sarin, SS Agarwal, R A Badwe, HB Tangaoankar, K.A Dinshaw |
2004 |
TMH |
16 |
Prospective neurological function, quality of life and Barthel's assessment in adult patients with primary brain tumours. R Jalali, A Bud, R Sar, R Kamble, S Parab, R Hawaldar |
2004 |
TMH |
17 |
Feasibility of concomitant electron boost (on Saturdays) in patients with locally advanced breast cancer treated with radiotherapy R Jalali, R Malde, A Budrukkar, R Sarin |
2004 |
TMH |
18 |
Para-aortic Lymph Node Staging and Evaluation of Treatment Outcome by 18F-fluorodeoxyglucose Positron Emission Tomography (FDG-PET) in Advanced Cancer Cervix. KA Dinshaw, SK Shrivastava, A Samuel, HB Tongaonkar, R Kerkar, A Maheshwari, S (Ghosh) Laskar. |
2004 |
TMH |
19 |
Elective versus Therapeutic Neck Dissection in the Treatment of Early Node Negative Squamous Cell Carcinoma of the Oral Cavity, AK D'cruz, D Chaukar, KA Pathak, M Deshpande, P Chaturvedi, P Pai, RL Bhalawat, S. (Ghosh) Laskar, JP Agarwal, KA Dinshaw |
2004 |
TMH |
20 |
Randomized Clinical trial to compare results of Concurrent chemo-radiation with surgery and post-operative radiotherapy. KA Pathak, M Deshpande, AK D'cruz, D Chaukar, P Chaturvedi, P Pai, RL Bhalawat, S. (Ghosh) Laskar, JP Agarwal, PM Parikh, VR Pai, KA Dinshaw |
2004 |
TMH |
21 |
A phase II trial of IRESSA in advanced Head & Neck cancers. D'cruz, D Chaukar, S. (Ghosh) Laskar, JP Agarwal, KA Dinshaw |
2004 |
Multicentric: ASTRA-ZENECA |
22 |
Radiotherapy Dose Escalation for Inoperable Ewing's Sarcoma/ PNET (EFT 2001 RT). S.Laskar, C.N.Nair, M.A.Muckaden, A.Puri, M.G.Agarwal, S.Gujral, S.Gupta, S.Banavali,P.Kurkure, S.K.Pai, S.Juvekar, N.Nair,D.D.Deshpande, S.K.Shrivastava, S.Basu. |
2004 |
DAE/ CTC |
23 |
Intensified Vincristine, Ifosfamide, Etoposide with Adriamycin, Cyclophosphamide, and Actinomycin D in the Treatment of Non-Metastatic Ewing's Family of Tumors. C.N.Nair, M.A.Muckaden, S.Gupta, S.Banavali, S.K.Pai, P.A.Kurkure, S.Laskar, A.Puri, M.G.Agarwal, S.Juvekar, T.Shet, M.Ramadwar, S.Desai, S.Agarwal, N.Nair, R.Havaldar. |
2004 |
TMH |
24 |
Intensive versus Routine follow-up for Soft Tissue Sarcomas. A.Puri, M.G.Agarwal, R.Badwe, R.Hawaldar, R.Mistry, C.S.Pramesh, S.Laskar, S.Gupta, N.Jambhekar, M.A.Muckaden, S.Juvekar. |
2004 |
TMH |
25 |
The Treatment and Characterization of Acute Lymphoblastic Leukemia in Children, Adolescents and Young Adults (INCTR 02-04). S.Banavali, P.Kurkure, C.N.Nair, P.M.Parikh,S.K.Pai, S.Gujral, M.A.Muckaden, S.Laskar, N.Merchant, S.Goswami, P.Amre, A.Paes, B.Kolhatkar, R.Hawaldar, N.Thomas. |
2004 |
TMH/ INCTR |
26 |
Concomitant and adjuvant Temozolomide with radical radiotherapy in children with brain stem glioma (brain stem glioma study). R.Jalali, P.Kurkure, R.Sarin, N.Merchant, T.Gupta |
2004 |
Hospital Intramural grant |
27 |
IMRT for Craniospinal irradiation (CSI) - will have preclinical component of dosimetric/modelling work followed by implementation and feasibility in 5 patients (IMRT-CSI study). R.Jalali, D.Sharma, R.Sarin, T.Gupta, Reena.P, S.K.Shrivastava, K.A.Dinshaw |
2004 |
DAE/CTC |
28 |
A phase II randomized trial Comparing IMRT with conventional radiation therapy in Stage IIB Carcinoma Cervix.SK Shrivastava, U Mahantshetty, DD Deshpande, S (Ghosh) Laskar, KA Dinshaw, RA Kinhikar, Sherly Saju, SV Jemima, HB Tongaonkar, S Gupta. |
2004 |
Varian Medical Systems LTD.USA |
29 |
Phase II study of 3-Dimentional Conformal Radiotherapy (3D-CRT) versus Intensity Modulated Radiotherapy (IMRT) for Squamous Cell Carcinoma of the Head & Neck (HNSCC).SG Laskar, T Gupta, JP Agarwal, SK Shrivastava, KA Dinshaw, PM Parikh, VR Pai, Reena Devi, S Deshpande, DD Deshpande. |
2005 |
Varian Ltd, USA |
30 |
Phase II study of 3-Dimentional Conformal Radiotherapy (3D-CRT) versus Intensity Modulated Radiotherapy (IMRT) for Squamous Cell Carcinoma of the Head & Neck (HNSCC).Gupta T, Laskar SG, Agarwal JP, Shrivastava SK, Dinshaw KA, Parikh PM, Pai VR, Reena Devi, Deshpande S, Deshpande DD. |
2005 |
Siemens Ltd., USA |
31 |
Para-aortic Lymph Node Staging and Evaluation of Treatment Outcome by 18F-fluorodeoxyglucose Positron Emission Tomography (FDG-PET) in Advanced Cancer Cervix. Dinshaw KA, Shrivastava SK, Samual A, Mahantshetty U, Laskar SG, Merchant NH, Gupta S, Tongaonkar HB, Rangrajan V, Purandare N. |
2005 |
DAE/CTC |
32 |
Comparative evaluation of different detectors for IMRT dosimetry. Deshpande DD, Kinhikar RA, Saju Sherley, Narayana SS, Sharma D, Shrivastava SK, Dinshaw KA. |
2005 |
Intramural / ACTREC |
33 |
Phase III Trial of Surgery followed by conventional radiotherapy (5#/Wk) versus concurrent chemoradiotherapy versus Accelerated radiotherapy (6#/Wk) in high risk, locally advanced, stage III & IVa, resectable, squamous cell carcinoma of oral cavity. Deshpande Mandar, D'Cruz AK, Pathak KA, Chaukar DA, Chaturvedi P, Pai P, Dinshaw KA, Bhalavat RL, Agarwal JP, Ghosh S, Pai VR, Mohandas K, Kane SV |
2005 |
DAE-CTC |
34 |
Temozolomide versus PCV in recurrent high grade gliomas (BR 12 Trial). A MRC conducted multicenter randomised trial -R Jalali (Collaborator from TMH). |
2005 |
MRC/ TMH |
35 |
Timing of systemic chemotherapy in patients with isolated locoregional recurrence of breast cancer. Nair R, Gupta S, Badwe R, Parmar V, Nadkarni M, Sarin R, Jalali R, Budrukkar AN, Hawaldar R |
2005 |
|
36 |
A phase III trial evaluating the role of chemotherapy as an adjuvant therapy for premenopausal women with endocrine responsive breast cancer who receive endocrine therapy (PERCHE trial). Parmar V, Badwe R, Nadkarni M, Nair R, Gupta S, Sarin R, Jalali R, Budrukkar AN, Hawaldar R |
2005 |
IBCSG |
37 |
A phase III trial evaluating the role of exemestrane plus GnRH analogue as an adjuvant therapy for premneopusal women with endocrine responsive breast cancer (TEXT trial) Parmar V, Badwe R, Nadkarni M, Nair R, Gupta S, Sarin R, Jalali R, Budrukkar AN, Hawaldar R |
2005 |
IBCSG |
TATA MEMORIAL HOSPITAL
Dr. E Borges Road, Parel, Mumbai - 400 012 India
Phone: +91-22- 24177000, 24177300, 24161413
Fax: +91-22-24146937
E-mail : msoffice@tmc.gov.in(for patient care and queries)/cash@tmc.gov.in(for accounts related)/fundraising@tmc.gov.in (for donors and donation related)/registrar@tmc.gov.in(for education and training)/hrd@tmc.gov.in(for administrative - HRD matters)
1165621 (357)