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  1. Basics
  2. Symptoms
  3. Diagnosis
  4. Treatment
  5. Preventions
  6. Knowledge Center

Our Approach

Sarcoma Center treats more osteosarcoma, or bone cancer, patients than any other cancer center in the nation. In fact, we are one of the few teams in the world devoted to bone cancer. Our experience and expertise help us produce outstanding outcomes, and our patients have an 80% five-year event-free survival rate.

We bring together a team of experts that includes specialists from many areas to give you personal, customized care. They focus their full attention on you, communicating and collaborating with each other and you to ensure carefully coordinated care. We use specialized therapies and technologies to be sure you receive the most advanced treatment with the least impact on your body.

If possible, it is best to have a biopsy to diagnose bone cancer at the same place you expect to receive treatment. It is essential to go to a specialized cancer center that has experience in osteosarcoma biopsy. If the biopsy is done incorrectly, it may make it more difficult later for the surgeon to remove all of the cancer without having to also remove all or part of the arm or leg with the tumor. A biopsy that is not done correctly may cause the cancer to spread.

As one of the world's leading cancer centers, we constantly work to discover new treatments and innovations. We helped pioneer:

Embolization for localized unresectable giant cell tumor of bone
Activity of interferon in metastatic giant cell tumor of bone
Limb-sparing surgery to help save arms and legs
Targeting a cell receptor known to play a part in the spread of cancer to the bones may enable chemotherapy drugs to be delivered directly to the cells

Bone cancer symptoms vary from person to person. They also depend on the size and location of the cancer.

If you have symptoms, they may include:

  • Pain
  • Swelling or tenderness in or near a joint
  • Difficulty with normal movement
  • Fatigue
  • Fever
  • Weight loss
  • Anemia (low red blood cell count)
  • Fractures

Having one or more of these symptoms does not mean you have bone cancer. However, it is important to discuss any symptoms with your doctor, since they may indicate other health problems.

one of the few centers in the world that has a program focused only on sarcoma, including bone cancer. We see more patients with sarcomas than most cancer centers, giving us a high level of experience. Our pathologists, who focus only on bone cancer, use the most advanced procedures and technology.

Accurate diagnosis is essential to successful treatment of bone cancer. The wrong kind of biopsy may make it more difficult later for the surgeon to remove all of the cancer without having to also remove all or part of the arm or leg with the tumor. A biopsy that is not done correctly may cause the cancer to spread.

If your doctor thinks you may have bone cancer, it’s important to go to a cancer center with a specialized bone cancer program. You should look for a program that does as many diagnostic procedures as possible. Also, if possible, the surgeon who performs the biopsy should also do the surgery to remove the cancer.

Bone Cancer Diagnosis

If you have symptoms that may signal bone cancer, your doctor will examine you and ask you questions about your health and your family history. One or more of the following tests may be used to find out if you have cancer and if it has spread. These tests also may be used to find out if treatment is working.

Biopsy: A biopsy, which removes a tiny piece of bone, is used to confirm the presence of cancer cells. This is the only way to find out for certain if the tumor is cancer or another bone disease. It is very important for the biopsy procedure to be done by a surgeon with experience in diagnosing and treating bone tumors.

There are two types of bone biopsy:

  • Needle biopsy: A long, hollow needle is inserted through the skin to the area of bone to be tested. The needle removes a cylindrical sample of bone to look at under a microscope.
  • Open or surgical biopsy: An incision (cut) is made, and the surgeon removes a tiny piece of bone for examination under a microscope.

Your doctor will decide which type of biopsy is best for you based on several factors, including the type and location of the tumor. If possible, the surgeon who performs the biopsy should also do the surgery to remove the cancer.

Imaging tests, which may include:

  • X-ray
  • CT or CAT (computed axial tomography) scans
  • MRI (magnetic resonance imaging) scans

Our Treatment Approach

MD Anderson is one of the most active bone cancer treatment programs in the world. We are committed to customizing your bone cancer care to include the most-advanced treatments with the least impact on your body.

Surgery is often the primary treatment for sarcoma. Studies show the best surgical outcomes are achieved by specialists with a high level of experience in the particular procedure. Because MD Anderson’s Sarcoma Center surgeons see only sarcoma patients – and more of them than most programs – they have a high level of expertise and experience that may translate into a higher chance for successful treatment.

MD Anderson surgeons usually can avoid the need for amputation of a limb. However, if it is necessary, we have specialized reconstructive surgeons, prosthetics and rehabilitation professionals to help make that transition.

Bone Cance Treatments

If you are diagnosed with bone cancer, your doctor will discuss the best options to treat it. This depends on several factors, including the type and stage of the cancer and your general health.

Your treatment for bone cancer will be customized to your particular needs. One or more of the following therapies may be recommended to treat the cancer or help relieve symptoms.

Like all surgeries, osteosarcoma surgery is most successful when performed by a specialist with a great deal of experience in the particular procedure. MD Anderson osteosarcoma surgeons are among the most skilled and recognized in the world. They perform a large number of surgeries for bone cancer each year, using the most advanced techniques that have the least impact on your body.

Bone Cancer Screening

Screening tests are important ways to find cancer if you are at risk but do not have symptoms. Unfortunately, no standardized screening tests have been shown to improve bone cancer outcomes.

If you are concerned about inherited family syndromes that cause bone cancer, we offer advancedgenetic testing to let you know your risk.

Bone Cancer Risk Factors

Anything that increases your chance of getting bone cancer is a risk factor. However, having risk factors does not mean you will get bone cancer. In fact, most people who develop bone cancer do not have any risk factors. If you have risk factors, it’s a good idea to discuss them with your health care provider.

Teenagers and young adults are at greatest risk of developing osteosarcoma, a type of bone cancer, because it often is associated with growth spurts. Some diseases that run in families can slightly increase the risk of bone cancer. These include:

  • Li-Fraumeni syndrome
  • Rothmund-Thompson syndrome
  • Retinoblastoma (an eye cancer of children)
  • Multiple osteochondromas

Other risk factors for bone cancer include:

  • Paget’s disease
  • Prior radiation therapy for cancer, especially treatment at a young age or with high doses of radiation
  • Bone marrow transplant

Contact Us

TATA MEMORIAL HOSPITAL
Dr. E Borges Road, Parel, Mumbai - 400 012 India
Phone: +91-22- 24177000, 24146750 - 55
Fax: +91-22-24146937
E-mail : msoffice@tmc.gov.in (for patient care and queries) / hrd@tmc.gov.in(for administrative - HRD matters)

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