Adult Haemato Lymphoid

PROJECT_NO PI_NAME PROJECT_TITLE CTRI_NO STATUS DEPARTMENT DMG
1627 Dr. Jayant Goda Radiation Dose Optimization in Diffuse large B- cell Lymphoma - A Randomised Phase III non- inferiority trial. CTRI/2016/11/007485 Active accrual and intervention ongoing Radiation Oncology Adult Haemato Lymphoid
1729 Dr. Hasmukh Jain A prospective observational study to determine the risk of Hepatitis B viral reactivation in adolescent and adult acute lymphoblastic leukemia/lymphoblastic lymphoma (ALL/LBL) with Occult Hepatitis B infection (OHBI). CTRI/2017/01/007747 Data Analysis ongoing Medical Oncology Adult Haemato Lymphoid
1755 Dr. Hasmukh Jain Role of IL-9 and Th9 cells in T cell lymphoma with cutaneous involvement CTRI/2017/04/008356 Active Enrollment ongoing Medical Oncology Adult Haemato Lymphoid
1979 Dr. Jayant Goda A dosimetric and clinical study of DIBH in Mediastinal Lymphomas: An exploratory observational study CTRI /2018/07/014847 Active accrual and intervention ongoing Radiation Oncology Adult Haemato Lymphoid
3209 Dr. Manju Sengar Hematological Cancers Consortium: HCC Leukemia Registry CTRI/2020/02/023455 Active Enrollment ongoing Medical Oncology Adult Haemato Lymphoid
3214 Dr. Hasmukh Jain A prospective observational cohort study to identify the utility of risk-based screening strategy for long term complications in adolescent and adult cancer survivors of leukemia and lymphoma. CTRI/2019/06/019880 Accrual completed and follow-up ongoing Medical Oncology Adult Haemato Lymphoid
3257 Dr. Nehal Khanna A Prospective Randomized Phase III Trial of Short Course Versus Long Course Local Radiotherapy in patients with Multiple Myeloma symptomatic for Pain (ProM) CTRI/2020/01/022975\t Active accrual and intervention ongoing Radiation Oncology Adult Haemato Lymphoid
3286 Dr. Tanuja Shet Classical Hodgkins lymphoma( CHL) with primary marrow presentation- does it use immune escape mechanism to hide ? Active enrollment ongoing Pathology Adult Haemato Lymphoid
3353 Dr. Bhausaheb Bagal Protocol No. - 20160372 : Post-marketing Phase 4 Study to Evaluate Safety, Tolerability, and Efficacy of Kyprolis® (Carfilzomib) in Indian Patients With Relapsed or Refractory Multiple Myeloma: A Prospective, Open-label, Non-comparative, Multicenter Study CTRI/2019/06/019535 Data Analysis ongoing Medical Oncology Adult Haemato Lymphoid
3380 Dr. Jayant Goda Total Marrow and Lymphoid Irradiation (TMLI) as conditioning regimen for peripheral stem cell transplant in high risk/ relapsed /refractory leukemias. CTRI/2019/11/022162 Active accrual and intervention ongoing Radiation Oncology Adult Haemato Lymphoid
3423 Dr. Hasmukh Jain A phase II study to evaluate the role of short-course Pomalidomide in maintaining treatment-free remission post tyrosine-kinase inhibitor (TKI) discontinuation in adult patients with chronic myeloid leukemia-chronic phase (CML-CP). CTRI/2020/10/028549 Active Enrollment ongoing Medical Oncology Adult Haemato Lymphoid
3465 Dr. Hasmukh Jain Phase I study to evaluate the feasibility and safety of addition of ruxolitinib to a standard BFM-90 regimen in adolescent/adult Ph-like ALL. CTRI/2021/02/031251 Active enrollment ongoing Medical Oncology Adult Haemato Lymphoid
3466 Dr. Hasmukh Jain A study to validate the Multinational Association of Supportive Care in Cancer (MASCC) antiemesis tool for adolescent and adult patients with hematological malignancies receiving chemotherapy. CTRI/2020/10/028252 Active Enrollment ongoing Medical Oncology Adult Haemato Lymphoid
3507 Dr. Manju Sengar A phase II randomized study to evaluate the efficacy of short-course RR CVEP regimen against short course EPOCH-RR in adolescent and adult seropositive Diffuse large B cell lymphoma CTRI/2020/10/028220 Active Enrollment ongoing Medical Oncology Adult Haemato Lymphoid
3508 Dr. Hasmukh Jain A pilot study of indigenously manufactured HCAR19 (2nd generation Anti-CD19-41BBCD3 (zeta) chimeric antigen receptor T-cell therapy) in adult patients with relapsed/refractory diffuse large B-cell lymphoma. CTRI/2021/04/032727 Accrual completed and follow-up ongoing Medical Oncology Adult Haemato Lymphoid
3552 Dr. Manju Sengar A phase II study to evaluate the activity of 177-Lu-DOTA Rituximab in adult patients with relapsed/refractory low-grade B-cell lymphomas. CTRI/2021/02/031578 Not started/Not initiated Medical Oncology Adult Haemato Lymphoid
3586 Dr. Hasmukh Jain A study to develop an artificial intelligence algorithm for predicting the outcomes of febrile neutropenia (FN) in adolescent and adults with haematological malignancies. CTRI/2021/11/037855 Active Enrollment ongoing Medical Oncology Adult Haemato Lymphoid
3620 Dr. Hasmukh Jain Evaluation of the safety and efficacy of generic low-dose Dasatinib for frontline therapy in chronic phase chronic myeloid leukemia - A multi-center phase II single arm study CTRI/2020/10/028317 Data Analysis ongoing Medical Oncology Adult Haemato Lymphoid
3621 Dr. Hasmukh Jain A phase III randomized study to compare a risk-stratified and response adapted strategy to ABVD regimen in adolescents and adults with advanced-stage Hodgkin lymphoma. CTRI/2020/12/030132 Accrual completed and intervention ongoing Medical Oncology Adult Haemato Lymphoid
3678 Dr. Manju Sengar Early T-cell precursor acute lymphoblastic leukaemia: Unravelling mechanisms of resistance and development of novel therapeutic strategies CTRI/2022/03/041157 Active Enrollment ongoing Medical Oncology Adult Haemato Lymphoid
3722 Dr. Prashant Tembhare A retrospective analysis of flow cytometric immunophenotypic characterization and T-cell clonality determination in T cell non-Hodgkin's lymphoma. Accrual completed and follow-up ongoing Hemato-pathology Adult Haemato Lymphoid
3754 Dr. Lingaraj Nayak An open label phase III randomized clinical trial of pomalidomide cyclophosphamide and dexamethasone versus pomalidomide dexamethasone in relapsed/ refractory multiple myeloma treated with lenalidomide and a proteasome Inhibitor. \tCTRI/2021/12/038872 Active Enrollment ongoing Medical Oncology Adult Haemato Lymphoid
3851 Dr. Hasmukh Jain A single-arm phase II study(DASLOW) to evaluate the ability to maintain molecular response with Reduced dose Dasatinib(70 mg once daily) in patients with De-Novo Philadelphia positive Acute Lymphoblastic Leukemia (Ph+ ALL) after achieving deep molecular response during the intensive phase of treatment CTRI/2022/08/044923 Active Enrollment ongoing Medical Oncology Adult Haemato Lymphoid
3856 Dr. Hasmukh Jain A prospective observational cohort study to evaluate the effectiveness and toxicities of standard regimen in elderly patients with De-Novo DLBCL. CTRI/2022/09/045751 Active Enrollment ongoing Medical Oncology Adult Haemato Lymphoid
3871 Dr. Bhausaheb Bagal Protocol No. - ACE-LY-312(D8227C00001) : A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of Acalabrutinib in Combination with Rituximab, Cyclophosphamide,_x000D_\nDoxorubicin, Vincristine, and Prednisone (R-CHOP) in Subjects <= 75 Years with Previously Untreated Non-Germinal Center Diffuse Large B-Cell Lymphoma CTRI/2022/03/041246 Accrual completed and follow-up ongoing Medical Oncology Adult Haemato Lymphoid
3936 Dr. Prashant Tembhare A retrospective study of the utility of new markers (CD148, CD180, CD200 and CD305) in the subtyping of mature B-cell non-Hodgkin lymphoma using flow cytometric immunophenotyping. Approved Hemato-pathology Adult Haemato Lymphoid
3980 Dr. Tanuja Shet Burkitt-like lymphoma with 11q aberration - study on incidence and behaviour in Indian patients 0 Active accrual and intervention ongoing Pathology Adult Haemato Lymphoid
4009 Dr. Hasmukh Jain A phase II study of indigenously manufactured HCAR19 (2nd generation Anti-CD19-4-1BB-CD3&zeta; chimeric antigen receptor T-cell therapy) in adolescent and adult patients with relapsed/refractory B-cell malignancies. CTRI/2022/12/048211 Accrual completed and follow-up ongoing Medical Oncology Adult Haemato Lymphoid
4026 Dr. Jayita Deodhar INTEGRATION OF SPECIALIST PALLIATIVE CARE IN HIGH-GRADE NON-HODGKIN'S LYMPHOMA PATIENTS (InSPeCt -HGNHL)- A Prospective observational study CTRI/2022/10/046652 Data Analysis ongoing Palliative Medicine Adult Haemato Lymphoid
4034 Dr. Manju Sengar A Phase I study of maintenance therapy with combination of pomalidomide and oral azacytidine for adult patients with Acute Myeloid Leukaemia (AML). CTRI/2023/09/057552 Active accrual and intervention ongoing Medical Oncology Adult Haemato Lymphoid
4075 Dr. Hasmukh Jain A novel Artificial Intelligence-based prognostic approach using PET-CT images and pathology images for advanced-stage Hodgkin Lymphoma CTRI/2024/02/062294 Data Analysis ongoing Medical Oncology Adult Haemato Lymphoid
4120 Dr. Prashant Tembhare Role of immune surveillance in the persistence of minimal/measurable residual disease (MRD) and pathogenesis of relapse in adult B-cell acute lymphoblastic leukemia (B-ALL) Active Enrollment ongoing Hemato-pathology Adult Haemato Lymphoid
4179 Dr. Manju Sengar A single centre prospective observational study to compare the outcomes and toxicities of Azacitidine + Venetoclax (AZA + VEN) with 3+7 induction chemotherapy (IC) with Cytarabine and Daunorubicin in patients with Acute Myeloid Leukemia (AML)_x000D_\n_x000D_\n CTRI/2023/06/053981 Active enrollment ongoing Medical Oncology Adult Haemato Lymphoid
4223 Dr. Tanuja Shet Incidence and prognostic value of EZH2 mutations in follicular lymphoma Case review/sample review ongoing (audit studies) Pathology Adult Haemato Lymphoid
4227 Dr. Manju Sengar Assessment of patient perceptions, resource utilisation and utility of tramadol as pre procedural analgesia in bone marrow aspiration and biopsy. CTRI/2024/01/062117. Active enrollment ongoing Medical Oncology Adult Haemato Lymphoid
4262 Dr. Akshay Baheti ROLE OF ARTIFICIAL INTELLIGENCE IN EVALUATION OF NCCT THORAX IN PATIENTS WITH FEBRILE NEUTROPENIA Data Analysis ongoing Radio-diagnosis Adult Haemato Lymphoid
4265 Dr. Sneha Shah BASELINE METABOLIC FDG PET/CT PARAMETERS AS A PROGNOSTICATON MARKER IN ADULT DIFFUSE LARGE B CELL LYMPHOMA (DLBCL). Data Analysis ongoing Nuclear Medicine Adult Haemato Lymphoid
4277 Dr. Shamali Poojary MORPHINE MOUTHWASH VERSUS KETAMINE MOUTHWASH FOR ACUTE PAIN IN PATIENTS OF HEMATOLYMPHOID CANCERS WITH CHEMOTHERAPY INDUCED ORAL MUCOSITIS - A RANDOMISED CONTROLLED STUDY _x000D_\n_x000D_\n CTRI/2024/01/062050 Active accrual and intervention ongoing Palliative Medicine Adult Haemato Lymphoid
4324 Dr. Lingaraj Nayak Protocol No. - CA057008 : A Phase 3, Two-stage, Randomized, Multicenter, Open-label Study Comparing CC-92480 (BMS-986348), Carfilzomib, and Dexamethasone (480Kd) Versus Carfilzomib and Dexamethasone (Kd) in Participants with Relapsed or Refractory Multiple Myeloma (RRMM) CTRI/2023/08/056910 Active enrollment ongoing Medical Oncology Adult Haemato Lymphoid
4351 Dr. Uma Sakhdeo A study of clinico-pathological parameters and PDL1 expression in Diffuse large B cell lymphoma involving the testis. Case review/sample review ongoing (audit studies) Pathology Adult Haemato Lymphoid
4403 Dr. Hasmukh Jain Risk-adapted PET-CT-guided Therapy for Adults with Newly Diagnosed Classical Hodgkin Lymphoma using ABVD and EACODD-14 Regimens (HL-Russia-1). NCT04638790 Not started/Not initiated Medical Oncology Adult Haemato Lymphoid
4478 Dr. Bhausaheb Bagal A Phase 1, First-in-Human, Multicenter, Open-Label, Dose Escalation and Dose-Expansion Study of Single-Agent ISB 2001 in Subjects with Relapsed/Refractory Multiple Myeloma Approved Medical Oncology Adult Haemato Lymphoid
4480 Dr. Alok Shetty Enhancing health record digitization using AI-powered ambient clinical intelligence solutions - a pilot study CTRI/2024/11/076365 Active enrollment ongoing Medical Oncology Adult Haemato Lymphoid
4513 Dr. Manju Sengar Phase III open labelled randomized controlled study to evaluate the optimal dose of all-trans retinoic acid in the treatment of acute promyelocytic leukemia. CTRI/2023/09/057990 Approved Medical Oncology Adult Haemato Lymphoid
4520 Dr. Manju Sengar Phase I/II study of BCMA directed humanised CAR-T cell therapy (hBCMA) in patients with relapsed/refractory Multiple myeloma. CTRI/2025/01/079364 Approved Medical Oncology Adult Haemato Lymphoid
4532 Dr. Hasmukh Jain A Phase III RCT comparing AVD+ low dose nivolumab versus ABVD using a risk-adapted strategy in newly diagnosed advanced stage classical Hodgkin lymphoma. CTRI/2024/03/063942 Ongoing Medical Oncology Adult Haemato Lymphoid
4551 Dr. Hasmukh Jain A multicentre Phase III randomized control trial to test the efficacy of targeted agents during induction and a response-adapted consolidation in adolescent and young adult patients with de-novo ALL_x000D_\n CTRI/2025/03/082015 Approved Medical Oncology Adult Haemato Lymphoid
4602 Dr. Manju Sengar Deploying Oncology Specific Telemedicine (TeleOPD) platform in the North- Eastern states of India- a pilot study_x000D_\n_x000D_\n CTRI/2025/02/080742 Approved Medical Oncology Adult Haemato Lymphoid
4644 Dr. Manju Sengar Integration of machine learning and genomics to predict outcomes for newly diagnosed,_x000D_\nrelapsed and refractory mature T-cell and NK-cell neoplasms. Approved Medical Oncology Adult Haemato Lymphoid
4685 Dr. Hasmukh Jain Phase II study of immunotherapy in combination with CAR T-cell therapy (ACTALY CEL) in adults, adolescents patients with relapsed/refractory DLBCL CTRI/2025/03/082608 Approved Medical Oncology Adult Haemato Lymphoid
4689 Dr. Amrita Guha IMAGING ANALYSIS OF PATTERNS OF RESPONSE ASSESSMENT IN PRIMARY CNS LYMPHOMA Approved Radio-diagnosis Adult Haemato Lymphoid
4701 Dr. Bhausaheb Bagal A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled Study Comparing the Efficacy and Safety of Golcadomide Plus R-CHOP Chemotherapy vs Placebo Plus R-CHOP Chemotherapy in Participants with Previously Untreated High-risk Large B-cell Lymphoma Ongoing Medical Oncology Adult Haemato Lymphoid
4718 Mrs. Anita D Souza A feasibility study of mindfulness meditation and fatigue in patients planned to receive chemotherapy for non-Hodgkin lymphoma in Tata Memorial Hospital Mumbai. CTRI/2025/06/088478 Approved Nursing Services Adult Haemato Lymphoid
4720 Dr. Jayita Deodhar INTEGRATION OF SPECIALIST PALLIATIVE CARE IN RELAPSED/REFRACTORY HEMATOLOGIC MALIGNANCIES UNDERGOING CAR-T CELL THERAPY: A PILOT SINGLE-ARM SINGLE-CENTER PROSPECTIVE OBSERVATIONAL STUDY_x000D_\n_x000D_\n CTRI/2025/05/086476 Approved Palliative Medicine Adult Haemato Lymphoid
4729 Dr. Hasmukh Jain A Phase 1, Open Label, Dose Escalation, Multicenter, First-in-Human (FIH) Study Evaluating the Safety, Pharmacokinetics and Pharmacodynamics of Oral AUR112 in Patients with Relapsed Advanced Lymphoma (ADITI-1) Approved Medical Oncology Adult Haemato Lymphoid
4739 Dr. Uma Sakhdeo EBV expression in Diffuse large B cell lymphoma-nodal and extranodal Approved Pathology Adult Haemato Lymphoid
4753 Dr. Kunal Gala Retrospective analysis of diagnostic accuracy and safety of image guided spleen biopsy. Approved Radio-diagnosis Adult Haemato Lymphoid
4759 Dr. Bhausaheb Bagal An Open Label, Multicenter, Phase IV Study of Teclistamab to Evaluate its Safety in Indian Participants with Relapsed and Refractory Multiple Myeloma who have previously received at least 3 prior lines of therapy including an Immunomodulatory agent, a Proteasome Inhibitor and an Anti-CD38 antibody and have demonstrated disease progression on the last therapy. CTRI/2025/05/086109 Approved Medical Oncology Adult Haemato Lymphoid
4926 Dr. Manju Sengar Novel and optimized de-intensified induction therapy in acute myeloid leukemia Approved Medical Oncology Adult Haemato Lymphoid
4952 Dr. Gaurav Salunke Evaluate the performance of plasma based metagenomic sequencing in detecting pathogens causing sepsis in Hematological cancer patients Approved Microbiology Adult Haemato Lymphoid